Pepto-Bismol Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD (2024)

Uses

This medication is used to treat occasional upset stomach, heartburn, and nausea. It is also used to treat diarrhea and help prevent travelers' diarrhea. It works by helping to slow the growth of bacteria that might be causing the diarrhea. This product should not be used to self-treat diarrhea if you also have a fever or blood/mucus in the stools. These could be signs of a serious health condition. Consult your doctor promptly for proper evaluation and treatment if you have these symptoms.This medication is used under a doctor's direction with other medication to treat stomach ulcers caused by a certain bacteria (Helicobacter pylori). Do not use this medication to self-treat ulcers. Bismuth subsalicylate is a salicylate. Salicylates can cause serious bleeding problems when used alone in patients with ulcers.Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.

How to use Pepto-Bismol Tablet, Chewable

Take this medication by mouth, usually as needed, as directed by the product package or as directed by your doctor. The dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this drug more often than directed. Do not take more of this medication than recommended for your age. There are many brands and forms of bismuth subsalicylate available. Read the dosing instructions carefully for each product because the dosing directions may be different between products.

If you are using the chewable tablets, chew each tablet well and swallow. If you are using the liquid form of this medication, shake the bottle well before each dose. Measure the dose carefully using a special measuring device/cup. Do not use a household spoon because you may not get the correct dose.

This medication may react with other medications (such as tetracycline antibiotics, chloroquine), preventing them from being fully absorbed by your body. Talk with your doctor or pharmacist about how to schedule your medications to prevent this problem.

If your doctor has directed you to use this medication daily, use it regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Tell your doctor if your condition lasts or gets worse. If you are taking this medication for diarrhea, tell your doctor if your diarrhea lasts more than 2 days.

Side Effects

Side effects from this medication are rare. The most common side effects are darkening of the stools and/or tongue. These effects are harmless and will disappear when you stop the medication.

If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Vomiting/diarrhea that doesn't stop may result in dehydration. Contact your doctor promptly if you notice any symptoms of dehydration, such as unusual decreased urination, unusual dry mouth/thirst, fast heartbeat, or dizziness/lightheadedness

Tell your doctor right away if you have any serious side effects, including: ringing ears, hearing loss.

This drug may rarely cause serious (rarely fatal) bleeding from the stomach or intestines. If you notice any of the following unlikely but serious side effects, stop taking this medication and consult your doctor or pharmacist right away: stomach/abdominal pain that doesn't go away, vomit that looks like coffee grounds, black/tarry/bloody stools.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

See also Uses section.

Before taking bismuth subsalicylate, tell your doctor or pharmacist if you are allergic to it; or if you are allergic to aspirin, to salicylates (such as salsalate), or to NSAIDs (such as ibuprofen, naproxen, celecoxib); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems (such as hemophilia), bloody/black/tarry stools, gout.

This medication may contain aspartame. If you have phenylketonuria (PKU) or any other condition that requires you to restrict your intake of aspartame (or phenylalanine), consult your doctor or pharmacist about using this medication safely.

Before having surgery, tell your doctors or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This drug contains an aspirin-like product (salicylate). Children and teenagers younger than 18 years should not take this product if they have chickenpox, flu, or any undiagnosed illness or if they have recently received a vaccine. In these cases, taking aspirin or aspirin-like products increases the risk of Reye's syndrome, a rare but serious illness.

Tell your doctor if you are pregnant or if you plan to become pregnant. This medication may harm an unborn baby and cause problems with normal labor/delivery. It is not recommended for use in pregnancy from 20 weeks until delivery. If your doctor decides that you need to use this medication between 20 and 30 weeks of pregnancy, you should use the lowest effective dose for the shortest possible time. You should not use this medication after 30 weeks of pregnancy. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. However, similar drugs pass into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breastfeeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug are: valproic acid, carbonic anhydrase inhibitors (such as acetazolamide), corticosteroids (such as prednisone), dichlorphenamide, methotrexate.

This medication may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Examples include anti-platelet drugs such as clopidogrel, "blood thinners" such as dabigatran/enoxaparin/warfarin, among others.

Check all prescription and nonprescription medicine labels carefully since many contain pain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen, or naproxen) that are similar to this drug and, if taken together, may increase your risk for side effects. Low-dose aspirin should be continued if prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually 81-162 milligrams a day). Consult your doctor or pharmacist for more details.

This medication may interfere with certain medical/lab tests (such as x-rays of the intestines using contrast dye), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.

Does Pepto-Bismol Tablet, Chewable interact with other drugs you are taking?

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Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: ringing ears, hearing loss.

Notes

If your doctor prescribes this medication for you, do not share it with others.

If you are taking this medication for diarrhea, drink plenty of water to decrease the risk of dehydration. Consult your doctor or pharmacist for more details.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not freeze. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

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Drug Survey

Have you ever purchased Pepto-Bismol Tablet, Chewable?

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

Pepto-Bismol Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD (2024)

FAQs

Why is it bad to take Pepto-Bismol? ›

Adverse effects are uncommon with recommended doses, but mild side effects can occur such as nausea, vomiting, and constipation. When the bismuth in Pepto Bismol mixes with sulfur in saliva and digestive fluids, a black substance (bismuth sulfide) is formed that can darken the tongue and feces temporarily.

Why is Pepto-Bismol banned in France? ›

Over-the-counter medicine for traveler's diarrhea is regulated, too. Pepto-Bismol is not sold in France due to a health scare in the 1970s. Imodium is sold in France only with a prescription.

What drugs should not be taken with Pepto-Bismol? ›

Cautions with other medicines
  • an anticoagulant – medicines that help to prevent blood clots.
  • tablets or other oral medicines for diabetes.
  • medicine for gout.
  • doxycycline or minocycline, or any other tetracycline antibiotics.

Can you take Pepto-Bismol with high blood pressure medication? ›

The combination may cause your blood pressure to increase. You may need a dose adjustment or your blood pressure checked more often. Also, if you are already taking the combination and stop taking bismuth subsalicylate, your blood pressure may decrease.

Why don t doctors recommend Pepto-Bismol? ›

Pepto-Bismol is typically safe for most people, but avoid it if you have certain health conditions. Pepto-Bismol may make them worse. Don't take Pepto-Bismol if you: are allergic to salicylates (including aspirin or NSAIDs such as ibuprofen, naproxen, and celecoxib)

What can I take instead of Pepto-Bismol? ›

What is the best upset stomach medicine?
Main uses
Pepto-BismolDiarrhea, nausea, and heartburn
MylantaHeartburn and gas
TumsHeartburn and indigestion
RolaidsHeartburn and indigestion
1 more row
Apr 24, 2024

Which age group should not use Pepto-Bismol? ›

Pepto Bismol products, like the Original Strength Liquid , are safe for adults and children 12 and older. For kids ages 2-11, turn to Pepto Kids, specially formulated for your little ones, and be sure to read the directions, as dosage instructions vary by your child's age and weight.

Is bismuth bad for you? ›

In the clinic, depending on the administration time of bismuth, its toxicity can be roughly divided into acute and chronic exposures. Both exposure doses can cause neurotoxicity, gastrointestinal toxicity, nephrotoxicity, hepatotoxicity, and increased bismuth concentration in blood.

Why have they stopped selling Pepto-Bismol in the UK? ›

Unfortunately, Pepto products are currently unavailable in the UK due to supply shortages. Efforts will continue to bring Pepto back to shelves as soon as possible, hopefully in 2023.

Can you drink water after Pepto? ›

You can eat and drink normally while taking Pepto-Bismol. However, it's best to avoid foods that seem to make your indigestion worse, like rich, spicy and fatty foods. Try to cut down on caffeinated drinks, such as tea, coffee, cola and energy drinks.

Is Pepto-Bismol or Tums better? ›

Pepto-Bismol has an average rating of 7.6 out of 10 from a total of 30 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 18% reported a negative effect. Tums Regular Strength has an average rating of 7.0 out of 10 from a total of 4 ratings on Drugs.com.

How long does Pepto stay in your system? ›

As it slowly makes its way out of your body you may see black poo. This side effect usually goes away when you stop taking the medicine but it may take several days. If your tongue or your poo is still black after you've stopped taking Pepto-Bismol for several days, speak to your doctor or a pharmacist.

Are there any negative side effects to Pepto-Bismol? ›

Pepto-Bismol side effects are typically mild. Nausea, a bitter taste, and a blackened tongue are possible. Rarely, Pepto-Bismol can cause serious side effects, such as Reye's syndrome in children and allergic reactions in those with aspirin allergies. It should be avoided if you're pregnant.

When should you not use Pepto? ›

Who may not be able to take Pepto-Bismol
  1. ever had an allergic reaction to bismuth subsalicylate or any of the other ingredients in Pepto-Bismol or Pepti Calm.
  2. ever had an allergic reaction to aspirin or any other medicine.
  3. diabetes.
  4. gout.

What are two blood pressure medications to avoid? ›

5 of the worst blood pressure medications
  • Beta blockers. Usually, beta blockers aren't used as first-choice therapies to lower blood pressure. ...
  • Loop diuretics. Furosemide (Lasix) is a type of diuretic (water pill) known as a loop diuretic. ...
  • Alpha blockers. ...
  • Vasodilators. ...
  • Alpha-2 agonists.
Feb 14, 2024

What does Pepto-Bismol do to your digestive system? ›

This medicine is used for heartburn and acid reflux, indigestion, diarrhoea and feeling sick (nausea). It works by protecting your stomach and the lower part of your food pipe from stomach acid. It is also a mild antacid, which helps reduce too much stomach acid and eases any discomfort.

Will Pepto-Bismol prolong a stomach virus? ›

However, in some cases, Pepto-Bismol may prolong a stomach virus. This is because diarrhea is the body's way of getting rid of the virus, and treating diarrhea may slow this process down. Most of the time, a stomach virus will resolve on its own with at-home care.

Can Pepto cause Reye's syndrome? ›

Aspirin (salicylate) is present in Pepto-Bismol® and children should not take it without first consulting their healthcare provider. Aspirin given during a viral illness or infection, like the flu, can cause symptoms of Reye's syndrome, but the direct cause of Reye's syndrome is unknown.

Does Pepto help food poisoning? ›

Pepto-Bismol® and Imodium® can help greatly with food poisoning and with the symptoms that come with it. Pepto-Bismol is great for helping with vomiting and nausea, while Imodium is an antidiarrheal that will help slow down the digestive process to help with diarrhea.

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