Encounter for therapeutic drug level monitoring (2024)

Table of Contents
Encounter for therapeutic drug level monitoring Encounter for blood-alcohol and blood-drug test Factors influencing health status and contact with health servicesNoteZ codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circ*mstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:(a)When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.(b)When some circ*mstance or problem is present which influences the person's health status but is not in itself a current illness or injury. Encounters for other specific health careApplicable ToCategories Z40-Z53 are intended for use to indicate a reason for care. They may be used for patients who have already been treated for a disease or injury, but who are receiving aftercare or prophylactic care, or care to consolidate the treatment, or to deal with a residual stateType 2 Excludesfollow-up examination for medical surveillance after treatment (Z08-Z09) Encounter for other aftercare and medical care Encounter for other specified aftercare Long term (current) drug therapy Persons encountering health services in other specified circ*mstances FAQs
  1. ICD-10-CM Codes
    2. ›
  2. Z00-Z99
    3. ›
  3. Z40-Z53
    4. ›
  4. Z51-
    5. ›
  5. 2024 ICD-10-CM Diagnosis Code Z51.81

Encounter for therapeutic drug level monitoring (1)

Encounter for therapeutic drug level monitoring

    2016 2017 2018 2019 2020 2021 2022 2023 2024 Billable/Specific Code POA Exempt
  • Z51.81 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursem*nt purposes.
  • The 2024 edition of ICD-10-CM Z51.81 became effective on October 1, 2023.
  • This is the American ICD-10-CM version of Z51.81 - other international versions of ICD-10 Z51.81 may differ.

Code Also

Code Also Help

A code also note instructs that 2 codes may be required to fully describe a condition but the sequencing of the two codes is discretionary, depending on the severity of the conditions and the reason for the encounter.

  • any long-term (current) drug therapy (

    ICD-10-CM Diagnosis Code Z79

    • Z79 Long term (current) drug therapy
      • Z79.0 Long term (current) use of anticoagulants and...
        • Z79.01 Long term (current) use of anticoagulants
        • Z79.02 Long term (current) use of antithrombotics/an...
      • Z79.1 Long term (current) use of non-steroidal anti...
      • Z79.2 Long term (current) use of antibiotics
      • Z79.3 Long term (current) use of hormonal contracep...
      • Z79.4 Long term (current) use of insulin
      • Z79.5 Long term (current) use of steroids
        • Z79.51 Long term (current) use of inhaled steroids
        • Z79.52 Long term (current) use of systemic steroids
      • Z79.6 Long term (current) use of immunomodulators a...
        • Z79.60 Long term (current) use of unspecified immuno...
        • Z79.61 Long term (current) use of immunomodulator
        • Z79.62 Long term (current) use of immunosuppressant
          • Z79.620 Long term (current) use of immunosuppressive ...
          • Z79.621 Long term (current) use of calcineurin inhibi...
          • Z79.622 Long term (current) use of Janus kinase inhib...
          • Z79.623 Long term (current) use of mammalian target o...
          • Z79.624 Long term (current) use of inhibitors of nucl...
        • Z79.63 Long term (current) use of chemotherapeutic a...
          • Z79.630 Long term (current) use of alkylating agent
          • Z79.631 Long term (current) use of antimetabolite age...
          • Z79.632 Long term (current) use of antitumor antibiot...
          • Z79.633 Long term (current) use of mitotic inhibitor
          • Z79.634 Long term (current) use of topoisomerase inhi...
        • Z79.64 Long term (current) use of myelosuppressive a...
        • Z79.69 Long term (current) use of other immunomodula...
      • Z79.8 Other long term (current) drug therapy
        • Z79.81 Long term (current) use of agents affecting e...
          • Z79.810 Long term (current) use of selective estrogen...
          • Z79.811 Long term (current) use of aromatase inhibito...
          • Z79.818 Long term (current) use of other agents affec...
        • Z79.82 Long term (current) use of aspirin
        • Z79.83 Long term (current) use of bisphosphonates
        • Z79.84 Long term (current) use of oral hypoglycemic ...
        • Z79.85 Long-term (current) use of injectable non-ins...
        • Z79.89 Other long term (current) drug therapy
          • Z79.890 Hormone replacement therapy
          • Z79.891 Long term (current) use of opiate analgesic
          • Z79.899 Other long term (current) drug therapy
    Z79.-)

Type 1 Excludes

Type 1 Excludes Help

A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as Z51.81. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

  • encounter for blood-drug test for administrative or medicolegal reasons (

    ICD-10-CM Diagnosis Code Z02.83

    Encounter for blood-alcohol and blood-drug test

      2016 2017 2018 2019 2020 2021 2022 2023 2024 Billable/Specific Code POA Exempt

    Use Additional

    • code for findings of alcohol or drugs in blood (R78.-)
    Z02.83)

The following code(s) above Z51.81 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

See Also
ICD-10 Code for Other specified disorders of teeth and supporting structures- K08.89- Codify by AAPCDisorder of teeth and supporting structures, unspecified2024 ICD-10-CM Diagnosis Code K04.7: Periapical abscess without sinusAcute embolism and thrombosis of unspecified deep veins of unspecified lower extremity

  • Applicable To annotations, or
  • Code Also annotations, or
  • Code First annotations, or
  • Excludes1 annotations, or
  • Excludes2 annotations, or
  • Includes annotations, or
  • Note annotations, or
  • Use Additional annotations

that may be applicable to Z51.81:

  • Z00-Z99

    2024 ICD-10-CM Range Z00-Z99

    Factors influencing health status and contact with health services

    Note

    • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circ*mstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
    • (a)When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
    • (b)When some circ*mstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

    Factors influencing health status and contact with health services
  • Z40-Z53

    2024 ICD-10-CM Range Z40-Z53

    Encounters for other specific health care

    Applicable To

    • Categories Z40-Z53 are intended for use to indicate a reason for care. They may be used for patients who have already been treated for a disease or injury, but who are receiving aftercare or prophylactic care, or care to consolidate the treatment, or to deal with a residual state

    Type 2 Excludes

    • follow-up examination for medical surveillance after treatment (Z08-Z09)

    Encounters for other specific health care
  • Z51

    ICD-10-CM Diagnosis Code Z51

    Encounter for other aftercare and medical care

      2016 2017 - Revised Code 2018 2019 2020 2021 2022 2023 2024 Non-Billable/Non-Specific Code

    Code Also

    • condition requiring care

    Type 1 Excludes

    • follow-up examination after treatment (Z08-Z09)
    Encounter for other aftercare and medical care
  • Z51.8

    ICD-10-CM Diagnosis Code Z51.8

    Encounter for other specified aftercare

      2016 2017 2018 2019 2020 2021 2022 2023 2024 Non-Billable/Non-Specific Code

    Type 1 Excludes

    • holiday relief care (Z75.5)
    Encounter for other specified aftercare

Approximate Synonyms

See Also
Partial loss of teeth, unspecified cause, unspecified class

  • Antihypertensive agent surveillance
  • Medication surveillance, antihypertensive
  • Monitoring growth hormone therapy
  • Monitoring growth hormone therapy done
  • Therapeutic drug monitoring
  • Therapeutic drug monitoring done

Clinical Information

  • (fer-e-sis) a procedure in which blood is collected, part of the blood such as platelets or white blood cells is taken out, and the rest of the blood is returned to the donor.
  • A procedure in which blood is collected, part of the blood such as platelets or white blood cells is taken out, and the rest of the blood is returned to the donor.
  • Any procedure in which blood is withdrawn from a donor, a portion is separated and retained and the remainder is returned to the donor.

Present On Admission

POA Help

"Present On Admission" is defined as present at the time the order for inpatient admission occurs — conditions that develop during an outpatient encounter, including emergency department, observation, or outpatient surgery, are considered POA.

  • Z51.81 is considered exempt from POA reporting.

ICD-10-CM Z51.81 is grouped within Diagnostic Related Group(s) (MS-DRG v41.0):

  • 949 Aftercare with cc/mcc
  • 950 Aftercare without cc/mcc

Convert Z51.81 to ICD-9-CM

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change

Code annotations containing back-references to Z51.81:

  • Code Also: Z79

    ICD-10-CM Diagnosis Code Z79

    Long term (current) drug therapy

      2016 2017 2018 2019 2020 2021 2022 2023 2024 Non-Billable/Non-Specific Code

    Code Also

    • any therapeutic drug level monitoring (Z51.81)

    Includes

    • long term (current) drug use for prophylactic purposes

    Type 2 Excludes

    • drug abuse and dependence (F11-F19)
    • drug use complicating pregnancy, childbirth, and the puerperium (O99.32-)

Diagnosis Index entries containing back-references to Z51.81:

  • Encounter (with health service) (for) Z76.89

    ICD-10-CM Diagnosis Code Z76.89

    Persons encountering health services in other specified circ*mstances

      2016 2017 2018 2019 2020 2021 2022 2023 2024 Billable/Specific Code POA Exempt

    Applicable To

    • Persons encountering health services NOS
    • therapeutic drug level monitoring Z51.81
  • Monitoring (encounter for)
    • therapeutic drug level Z51.81

ICD-10-CM Codes Adjacent To Z51.81

Z49.31 Encounter for adequacy testing for hemodialysis

Z49.32 Encounter for adequacy testing for peritoneal dialysis

Z51 Encounter for other aftercare and medical care

Z51.0 Encounter for antineoplastic radiation therapy

Z51.1 Encounter for antineoplastic chemotherapy and immunotherapy

Z51.11 Encounter for antineoplastic chemotherapy

Z51.12 Encounter for antineoplastic immunotherapy

Z51.5 Encounter for palliative care

Z51.6 Encounter for desensitization to allergens

Z51.8 Encounter for other specified aftercare

Z51.81 Encounter for therapeutic drug level monitoring

Z51.89 Encounter for other specified aftercare

Z52 Donors of organs and tissues

Z52.0 Blood donor

Z52.00 Unspecified blood donor

Z52.000 Unspecified donor, whole blood

Z52.001 Unspecified donor, stem cells

Z52.008 Unspecified donor, other blood

Z52.01 Autologous blood donor

Z52.010 Autologous donor, whole blood

Z52.011 Autologous donor, stem cells

Reimbursem*nt claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

Encounter for therapeutic drug level monitoring (2024)

FAQs

What does "encounter for therapeutic drug level monitoring" mean? ›

Therapeutic drug monitoring. Therapeutic drug levels are lab tests to look for the amount of a drug or medicine in the blood. Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand.

Discover More ›
What is encounter for therapeutic drug level monitoring ICD 10 Z51 81? ›

Encounter for therapeutic drug level monitoring. Z51. 81 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursem*nt purposes. The 2024 edition of ICD-10-CM Z51.

See Details ›
What is therapeutic drug monitoring Quizlet? ›

Therapeutic drug monitoring (TDM) involves the constant monitoring of the blood concentration of a drug, in a patient, to determine the right scheme. It evaluates the ADME of the drug.

Read The Full Story ›
What does therapeutic level of drug mean? ›

Your results will show if medicine levels in your blood are in a range that is medically helpful but not dangerous. This is called the therapeutic range. The range varies depending on the type of medicine and your own health needs. If your results are not in this range, your provider may need to adjust your dosages.

Get More Info Here ›
What is the normal range for therapeutic drug monitoring? ›

Therapeutic drug monitoring
DrugTherapeutic range (mg/L)
Theophylline10 – 20
Phenytoin10 – 20
Carbamazepine5.0 – 12
Sodium valproate50 – 100
13 more rows

Tell Me More ›
What affects therapeutic drug monitoring? ›

Concentrations can be affected by factors such as drug interactions, protein binding, drug metabolism and patient factors such as age, malabsorption and non-compliance. Also, liver and/or renal impairment may reduce clearance and increase the risk of toxicity, especially after a dose increase.

Get More Info Here ›
What is diagnosis code Z51 8? ›

ICD-10 code Z51. 8 for Encounter for other specified aftercare is a medical classification as listed by WHO under the range - Factors influencing health status and contact with health services .

Keep Reading ›
Can Z51-89 be a primary diagnosis? ›

code Z51. 89 can be used as the primary diagnosis. Providers are required to submit a secondary diagnosis code to describe the origin of the impairment for which rehabilitative therapy is needed when one of these V-codes or Z51. 89 is billed as a primary diagnosis.

Read The Full Story ›
What is the ICD-10 code for encounter for drug test? ›

2024 ICD-10-CM Diagnosis Code Z02. 83: Encounter for blood-alcohol and blood-drug test.

Learn More ›
What sample is used for therapeutic drug monitoring? ›

The role of many drug assay laboratories is to measure the concentration of a therapeutic drug in a blood sample and relate this number to a therapeutic range published in the literature.

Read On ›

What are the major considerations in therapeutic drug monitoring? ›

The pharmacological response of a patient to a given dosage regime is determined by several factors, including patient compliance, bioavailability, serum (or whole blood) drug level, rate of elimination, and the access of the drug to the receptor site as well as the receptor sensitivity.

Learn More ›
What circ*mstance is therapeutic drug monitoring TDM typically used for? ›

The indications for TDM are suspected dose-related toxicity, suspected noncompliance, acute overdose, chronic abuse, reduced kidney or liver function, potential interaction with other drugs, evaluation of absorption, and optimalization of treatment.

Get More Info Here ›
What does therapeutic drug level monitoring mean? ›

Therapeutic drug monitoring (TDM) is the clinical practice of measuring specific drugs at designated intervals to maintain a constant concentration in a patient's bloodstream, thereby optimizing individual dosage regimens.

Discover More ›
What is maximum therapeutic drug level? ›

The “maximum recommended therapeutic dose” (MRTD) for a drug is the upper limit beyond which efficacy is not increased and side effects begin to outweigh beneficial effects. MRTD is empirically derived from human clinical trials, and provides a threshold for dose‐related side effects.

Tell Me More ›
When should carbamazepine levels be checked? ›

When checking carbamazepine levels in a patient on a regular medication regimen, the specimen should be drawn immediately prior to next carbamazepine dose (trough).

Discover More ›
What do you mean by therapeutic drug monitoring? ›

Therapeutic drug monitoring (TDM) is the clinical practice of measuring specific drugs at designated intervals to maintain a constant concentration in a patient's bloodstream, thereby optimizing individual dosage regimens.

See Details ›
When should therapeutic drug monitoring be considered for a drug? ›

TDM is valuable when the drug in question has a narrow therapeutic index and toxicity may be encountered at a concentration slightly above the upper end of the therapeutic range.

Get More Info Here ›
What are the clinical indications of therapeutic drug monitoring? ›

The goals are to individualize drug dosing for optimal benefit and assess drug efficacy and safety. TDM is indicated when drugs have a narrow therapeutic index, clinical response is difficult to assess, or metabolism varies between patients.

Explore More ›
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