Coronary heart disease - Causes (2024)

Coronary heart disease (CHD) is usually caused by a build-up of fatty deposits (atheroma)on the walls of the arteries around the heart (coronary arteries).

The build-up of atheroma makes the arteries narrower, restricting the flow of blood to the heart muscle. This process is called atherosclerosis.

Your risk of developing atherosclerosis is significantly increased if you:

Other risk factors for developing atherosclerosis include:

  • beingobese or overweight
  • having a family history of CHD

Smoking

Smoking is a major risk factor for coronary heart disease. Both nicotine and carbon monoxide (from the smoke) put a strain on the heart by making it work faster. They also increase your risk of blood clots.

Other chemicals in cigarette smoke can damage the lining of your coronary arteries, leading to furring of the arteries. Smoking significantly increases your risk of developing heart disease.

Read about how to quit smoking and stop smoking treatments.

High blood pressure

High blood pressure (hypertension) puts a strain on your heart and can lead to CHD.

Read more abouthigh blood pressure.

Find further information on understanding your blood pressure on the Blood Pressure UK website.

High cholesterol

Cholesterol is a fat made by the liver from the saturated fat in your diet. It's essential for healthy cells, but too much in the blood can lead to CHD.

Read more about high cholesterol.

High lipoprotein (a)

Like cholesterol, lipoprotein (a), also known as LP(a), is a combination of fat and protein made by the liver. It's a known risk factor for cardiovascular disease and atherosclerosis.

The level of LP(a) in your blood is inherited from your parents. It's not routinely measured, but screening is recommended for people with a moderate or high risk of developing cardiovascular disease.

Find more information about high lipoprotein (a) on the Heart UK website.

Lack of regular exercise

If you're inactive, fatty deposits can build up in your arteries.

If the arteries that supply blood to your heart become blocked, it can lead to a heart attack. If the arteries that supply blood to your brain are affected it can cause a stroke.

Read about the physical activity guidelines for adults aged 19 to 64.

Diabetes

A high blood sugar level may lead to diabetes, which can more than double your risk of developing CHD.

Diabetes can lead to CHD because it may cause the lining of blood vessels to become thicker, which can restrict blood flow.

Thrombosis

A thrombosis is a blood clot in a vein or artery.

If a thrombosis develops in a coronary arteryit prevents the blood supply from reaching the heart muscle. This usually leads to a heart attack.

Page last reviewed: 17 January 2024
Next review due: 17 January 2027

Coronary heart disease - Causes (2024)

FAQs

Coronary heart disease - Causes? ›

Coronary artery disease is caused by the buildup of fats, cholesterol and other substances in and on the walls of the heart arteries. This condition is called atherosclerosis. The buildup is called plaque. Plaque can cause the arteries to narrow, blocking blood flow.

What are the main causes of coronary heart disease? ›

  • Smoking. Smoking is a major risk factor for coronary heart disease. ...
  • High blood pressure. High blood pressure (hypertension) puts a strain on your heart and can lead to CHD. ...
  • High cholesterol. ...
  • High lipoprotein (a) ...
  • Lack of regular exercise. ...
  • Diabetes. ...
  • Thrombosis.

Which of the following is a cause of coronary heart disease? ›

What is the most common cause of coronary artery disease? Most often, atherosclerosis causes coronary artery disease. Atherosclerosis occurs when a waxy substance called plaque builds up in your coronary arteries. Over time, the plaque buildup narrows your coronary arteries and restricts blood flow.

What causes coronary heart disease nasm? ›

Today, it is well-accepted that Cardiovascular Disease (CVD), the leading cause of death in the U.S., is rooted in inflammation, insulin resistance, oxidative stress (rusting), hormonal imbalances, and exposure to toxins.

What is coronary artery disease often caused by? ›

Coronary artery disease is often caused by cholesterol, a waxy substance that builds up inside the lining of the coronary arteries, forming plaque. This plaque buildup can partially or totally block blood flow in the large arteries of the heart.

How long can you live with coronary heart disease? ›

At age 50, the average woman can expect to live 7.9 years with heart disease, while the figure for the average man is 6.7 years. At each age, women are more likely to spend time diagnosed with disease and without a heart attack. Men at every age can expect to spend more years after a heart attack than women.

How did I get coronary heart disease? ›

Causes of coronary heart disease (CHD)

Atherosclerosis can be caused by lifestyle factors, such as smoking and regularly drinking excessive amounts of alcohol. You're also more at risk of getting atherosclerosis if you have conditions like high cholesterol, high blood pressure (hypertension) or diabetes.

What is the most common cause of coronary syndrome? ›

Possible causes
  • Infections. People with ME/CFS often begin with an illness similar to the flu. ...
  • Immune system changes. It is possible ME/CFS is caused by changes in a person's immune system or how it responds to infection or stress. ...
  • Stress affecting body chemistry. ...
  • Changes in energy production. ...
  • Possible genetic link.
May 10, 2024

What are the causes of coronary syndrome? ›

ACS is a manifestation of CHD (coronary heart disease) and usually a result of plaque disruption in coronary arteries (atherosclerosis). The common risk factors for the disease are smoking, hypertension, diabetes, hyperlipidemia, male sex, physical inactivity, family obesity, and poor nutritional practices.

What are the causes of cardiac disease? ›

What are the risk factors for cardiovascular disease? The most important behavioural risk factors of heart disease and stroke are unhealthy diet, physical inactivity, tobacco use and harmful use of alcohol.

Can coronary heart disease be cured? ›

It is possible to prevent coronary heart disease by maintaining a healthy lifestyle and, for some people taking medications. Coronary heart disease cannot be cured, but it can be managed to reduce your symptoms and your risk of experiencing serious complications.

What is the number one cause of heart disease? ›

A buildup of fatty plaques in the arteries (atherosclerosis) is the most common cause of coronary artery disease. Risk factors include a poor diet, lack of exercise, obesity and smoking. Healthy lifestyle choices can help lower the risk of atherosclerosis.

How to reverse coronary artery disease? ›

It is not currently possible to completely reverse or cure coronary artery disease. However, scientists continue to research it. There are several lifestyle methods that can help prevent CAD or reduce symptoms. These include getting enough physical activity, consuming a diet low in saturated fats, and avoiding smoking.

What is the most common coronary heart disease? ›

Obstructive coronary artery disease occurs when your coronary arteries gradually narrow due to plaque buildup, also known as atherosclerosis. It's the type of coronary artery disease that's most common and well-known. As the artery narrowing worsens, it can eventually cut off blood flow to your heart.

What foods cause plaque buildup in arteries? ›

The study, published Aug. 13 in Science, suggests that consuming food rich in saturated fat and choline - a nutrient found in red meat, eggs and dairy products - increases the number of metabolites that build plaques in the arteries.

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