Common questions about mebendazole (2024)

How does mebendazole work?

Mebendazole kills worms that cause gut infections such as threadworm (sometimes known as pinworm) and other less common worm infections (whipworm, roundworm and hookworm).

It works by stopping the worms using sugar (glucose). Without glucose, the cells of the worms lose their energy supply and quickly die.

Mebendazole does not kill the eggs of the worm. This is why you may need to take another dose 2 weeks later to help prevent reinfection.

How long does it take to work?

The medicine should start to work straight away but it may take several days to kill all the worms.

It's important to take the medicine as a pharmacist or doctor tells you. Do not stop early if you have been told to take it for several days.

Mebendazole does not kill the worms' eggs, and these can cause you to get worms again and pass it on to other people.

A doctor or pharmacist may advise you to take mebendazole again after 2 weeks, to stop the worms from coming back.

Is it safe to take repeat doses if worms keep coming back?

Mebendazole does not kill the worms' eggs, and these can cause reinfection and also infect other people.

A doctor or pharmacist may advise you to take mebendazole again after 2 weeks, to stop reinfection. However, if the infection comes back, speak to a doctor for advice.

It's also important to have good personal hygiene to stop the worms coming back.

A doctor or pharmacist may also advise that everyone in your house is treated with mebendazole.

Will it affect my contraception?

Mebendazole does not stop any type of contraception from working, including the combined pill, progestogen-only pill or emergency contraception.

But if mebendazole gives you severe diarrhoea for more than 24 hours, your contraceptive pills may not protect you from pregnancy.

If this happens, follow the instructions in the leaflet that comes with your contraceptive pills.

Find out more:

Can I drive or ride a bike?

Yes. Mebendazole should not affect you being able to drive or cycle.

Can I drink alcohol while taking mebendazole?

Yes, you can drink alcohol while taking mebendazole.

Is there any food or drink I need to avoid?

You can eat and drink normally while taking mebendazole.

It's important to remember to wash your hands and scrub under your fingernails before eating. This removes any eggs and stops the infection spreading or coming back.

Are there any lifestyle changes that can help with threadworms?

It's important to have good personal hygiene to stop threadworms from coming back, especially in babies and children under 2 years of age.

It's important to:

  • wash your hands and scrub under your fingernails – particularly before eating, after using the toilet or after changing nappies
  • encourage children to wash their hands regularly
  • bathe or shower every morning
  • rinse toothbrushes before using them
  • keep fingernails short
  • wash sleepwear, sheets and towels regularly
  • disinfect kitchen and bathroom surfaces
  • vacuum regularly and dust using a damp cloth
  • make sure children wear underwear at night and change them in the morning

Page last reviewed: 4 August 2022
Next review due: 4 August 2025

Common questions about mebendazole (2024)

FAQs

Common questions about mebendazole? ›

Wash hands and fingernails often, especially before eating and after using the toilet. Wash all fruits and vegetables thoroughly. Cook them well. Clean the bedroom floor by vacuuming or damp mopping for several days after treatment with this medicine.

What is the patient advice on mebendazole? ›

Wash hands and fingernails often, especially before eating and after using the toilet. Wash all fruits and vegetables thoroughly. Cook them well. Clean the bedroom floor by vacuuming or damp mopping for several days after treatment with this medicine.

What is mebendazole mainly active against? ›

Mebendazole is an antihelmintic used for the treatment of pinworms, whipworms, hookworms, and roundworms.

What happens if you take too much mebendazole? ›

If you take too much

Taking an extra dose of mebendazole is unlikely to harm you. However, you may get side effects such as: stomach cramps. feeling or being sick (nausea or vomiting)

What does mebendazole not treat? ›

Mebendazole will not treat a viral infection such as the flu or a common cold. You may need to take this medicine for 1 to 3 days, depending on the condition you are treating. However, it could take as long as 3 weeks before the infection is completely cleared.

What can you not take with mebendazole? ›

Include all brand names and combination drug names.
  • carbamazepine.
  • cimetidine.
  • fosphenytoin.
  • metronidazole.
  • phenobarbital.
  • phenytoin.
  • primidone.
  • ritonavir.

How quickly does mebendazole work? ›

Key facts. You'll usually take mebendazole as a single dose to treat threadworms, but you might need to take it for around 3 days for some other types of worm infection. It starts to work straight away but it may take several days to kill all the worms.

Is mebendazole hard on the liver? ›

Mebendazole when given for prolonged periods in high doses has been associated with elevations in serum enzyme levels, and rare instances of acute, clinically apparent liver injury have been linked to its use.

How toxic is mebendazole? ›

Mebendazole sometimes causes diarrhea, abdominal pain, and elevated liver enzymes. In rare cases, it has been associated with a dangerously low white blood cell count, low platelet count, and hair loss, with a risk of agranulocytosis in rare cases.

Does mebendazole affect gut bacteria? ›

Gut microbiota diversity increased after Enterobius infection, and it peaked after administration of mebendazole. At the phylum level, pinworm infection and mebendazole deworming were associated with a decreased relative abundance of Fusobacteria and an increased proportion of Actinobacteria.

Why is mebendazole no longer available? ›

Why is Mebendazole discontinued? Mebendazole was discontinued in 2011 due to the poor tissue penetration of Mebendazole and the current availability of albendazole and not for safety or efficacy reasons, stated by the Federal Register determination.

Are worms still alive after mebendazole? ›

Mebendazole does not kill the worms' eggs, and these can cause you to get worms again and pass it on to other people. A doctor or pharmacist may advise you to take mebendazole again after 2 weeks, to stop the worms from coming back.

Is there anything stronger than mebendazole? ›

lumbricoides, albendazole is superior to mebendazole for treating hookworm, and mebendazole slightly outperforms albendazole with regard to treating T. trichiura. To achieve high CRs against hookworm and T. trichiura infections, triple dose regimens should be considered.

What is the recommendation for mebendazole? ›

Dosing of mebendazole for common FDA indications are listed below: Roundworm (Ascaris lumbricoides): 100 mg twice daily (morning and night) for three consecutive days.

What are the guidelines for mebendazole? ›

Adults and children 2 years of age and older—100 milligrams (mg) two times a day, morning and evening, for 3 consecutive days. Treatment may need to be repeated in 3 weeks. Children younger than 2 years of age—Use and dose must be determined by your doctor.

What is the nursing implications for mebendazole? ›

Pregnancy & Breastfeeding

Mebendazole can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Is mebendazole well tolerated? ›

Mebendazole is generally well-tolerated. Patients with severe worm infestation may have diarrhoea, vomiting, or abdominal pain as the worms are killed and excreted. Other side effects may include drowsiness, itching, headache, and dizziness.

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